| 产品编号 | IHC0472H |
| 英文名称 | Human NPHS2 Ready-To-Use IHC Kit |
| 中文名称 | 人肾小球裂孔膜蛋白PDCN即用型免疫组化试剂盒 |
| 别 名 | AI790225; NPHS2; podocin; nephrosis 2; idiopathic; steroid resistant; NPHS2 gene; PDCN; Podocin; SRN1; PODO_HUMAN |
| 适用样品基质 | FFPE tissue |
| 保存条件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
| 产品介绍 |
The pathological conditions of SRN1 correlate well with mutations at the NPHS2 gene, where expression of a protein known as Podocin occurs. Abnormal or inefficient signaling through Podocin protein-dependent networks contributes to the development of podocyte dysfunction and proteinuria. The human NPHS2 gene maps to chromosome 1q25-q31 and encodes a 383 amino acid protein. Podocin is an integral membrane protein that appears to fold into a hairpin-like structure with intracellular amino- and carboxy-termini. Transmembrane and cytoplasmic portions of Podocin share homology to the corresponding regions of the stomatin family proteins. Expression of high-order oligomers of Podocin in glomerular podocytes may reflect a scaffolding function that influences proper function of the glomerular filtration barrier, which is necessary for renal stability. SWISS: Q9NP85 Gene ID: 7827 |
| 产品图片 |
Immunohistochemical analysis of paraffin embedded human kidney tissue slide using IHC0472H (Human NPHS2 IHC Kit).
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| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
