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产品中心-北京博奥森生物技术有限公司
Recombinant human IL-1RA protein, C-His (bs-42555P)
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说明书: 100ug  500ug  
100ug/2980.00元
500ug/9500.00元
大包装/询价

产品编号 bs-42555P
英文名称 Recombinant human IL-1RA protein, C-His
中文名称 重组人白介素-1受体拮抗剂
别    名 Interleukin-1 receptor antagonist; ICIL 1RA; IL1 inhibitor; ICIL1RA; IL1F3; IL1RN; IRAP; IL1RA_HUMAN;  
克 隆 号
理论分子量 18.3 kDa
检测分子量
性    状 Liquid
浓    度 >1mg/ml
纯    度 >90% as determined by SDS-PAGE
缓 冲 液 20mM Tris-Hcl (pH=8.0) with 150mM NaCL
保存条件 Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 IL-1RA is a member of the interleukin 1 cytokine family. IL1Ra is secreted by various types of cells including immune cells, epithelial cells, and adipocytes, and is a natural inhibitor of the pro-inflammatory effect of IL1β. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.

SWISS:
P18510

Gene ID:
3557

    L-lra-重组人白介素-1受体拮抗剂,通过与白细胞介素-1的Ⅰ型和Ⅱ型受体结合,特异性地阻断白细胞介素-1的生物学作用。白介素1受体拮抗剂(IL-1Ra)是体内天然的一种对IL-1有拮抗作用的细胞因子。国际上对其的研究愈来愈受到重视。 重组人白介素1受体拮抗剂(rhIL-1Ra)作为一种生物制剂已经FDA批准应用于临床治疗细胞因子。     重组白介素1受体拮抗剂,分子量约17kD,纯度大于98%。
产品图片
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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