扫码关注公众号           扫码咨询技术支持           扫码咨询技术服务
  
客服热线:400-901-9800  客服QQ:4009019800  技术答疑  技术支持  质量反馈  人才招聘  关于我们  联系我们
产品中心-北京博奥森生物技术有限公司
Recombinant human IL-18 protein (Active, E.coli) (bs-48056P)
订购热线:400-901-9800
订购邮箱:sales@bioss.com.cn
订购QQ:  400-901-9800
技术支持:techsupport@bioss.com.cn
说明书: 10ug  50ug  500ug
10ug/800.00元
50ug/2400.00元
500ug/9600.00元
大包装/询价
产品编号 bs-48056P
英文名称 Recombinant human IL-18 protein (Active, E.coli)
中文名称 重组人白细胞介素18
别    名 Interleukin-18; Iboctadekin; Interferon gamma-inducing factor; IFN-gamma-inducing factor; Interleukin-1 gamma; IL-1 gamma;GIF; IL-1g; IL1F4; MGC12320  
克 隆 号
理论分子量 18.2 kDa
检测分子量
性    状 Lyophilized
纯    度 ≥ 95% as determined by SDS-PAGE.
缓 冲 液 Lyophilized from 0.22μm-filtered solution in PBS, 5% mannital, 0.01% Tween 80, pH7.4
保存条件 Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 36 months at -20℃ to -80℃ in lyophilized state. 6 months at -20℃ to -80℃ under sterile conditions after reconstitution. 7-10 days at 2℃ to 8℃ under sterile conditions after reconstitution
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 IL18 (IFN-gamma-inducing factor, IGIF) is a novel pro-inflammatory cytokine that augments natural killer (NK) activity in spleen cells. This cytokine can induce the IFN-gamma production of T cells. The combination of this cytokine and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its biological activity.

SWISS:
Q14116

Gene ID:
3606

IL-18是巨噬细胞分泌的一个重要因子,它具有多种免疫功能,能诱导产生IFNγ,无论在病毒感染早期或特异性细胞免疫应答效应阶段都会出现,因此IL-18主要参与免疫应答及炎性细胞浸润的改变。Interleukin-18 又称inteferon-gamma inducing factor(IGIF),在辅助T细胞的应答反应中起重要作用。IL-18和IL-1一起,既参与先天免疫,又是后天免疫的构成因素。
版权所有 2004-2023 www.bioss.com.cn 北京博奥森生物技术有限公司
通过国际质量管理体系ISO 9001:2015 GB/T 19001-2016    认证编号: 00122Q31509R1M/1100
京ICP备05066980号-1         京公网安备110107000727号