| 产品编号 | V9001 |
| 英文名称 | Human Thyroglobulin Mouse mAb |
| 中文名称 | 人甲状腺球蛋白单克隆抗体 |
| 别 名 | THYG_HUMAN; TG; AITD 3; AITD3; hTG; TDH3; Tgn |
| 克 隆 号 | 1B5 |
| 理论分子量 | 660 kDa |
| 检测分子量 | |
| 性 状 | Liquid |
| 纯 度 | >90% as determined by SDS-PAGE |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
Thyroglobulin is the glycoprotein precursor of the iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3). Thyroglobulin is obtained from the thyroid gland and exhibits the general properties of the globulins. The human thyroglobulin (hTG) is a high molecular weight glycoprotein (605 kDa) found in the thyroid follicular cells. It plays a central role in the uptake, incorporation, and regulated biosynthesis of thyroid hormones, T4 and T3. Thyroid disorders are, in large part, due to autoimmune origin, and anti thyroglobulin autoantibodies were the first factor to be discovered. Anti hTG is found in all thyroid autoimmune diseases (Hashimoto's thyroiditis, Graves' diseases), with the highest level observed in Hashimoto's thyroiditis. Anti hTG is also characteristic of thyroid cancer, and its determination can be used for the follow up of cancer patients. SWISS: P01266 Gene ID: 7038 用作生产碘化甲状腺激素甲状腺素（T4）和三碘甲状腺素（T3）的底物。 T3和T4的合成涉及对TG /甲状腺球蛋白的选定酪氨酸残基加碘，然后在甲状腺滤泡内腔中进行氧化偶联。 在TG重新内在化和溶酶体介导的蛋白水解之后，T3和T4从多肽主链释放，导致它们分泌到血液中。 一个二聚体产生7个甲状腺激素分子。 |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
