| 产品编号 | bs-42580P |
| 英文名称 | Recombinant human FGF-8B protein, N-His |
| 中文名称 | 重组人成纤维细胞生长因子8蛋白 |
| 别 名 | AIGF; Androgen induced growth factor; Androgen-induced growth factor; FGF 8; FGF-8; FGF8; Fibroblast growth factor 8(androgen induced); Fibroblast growth factor 8 precursor; HBGF 8; HBGF-8; HBGF8; FGF8_HUMAN; |
| 克 隆 号 | |
| 理论分子量 | 24.8 kDa |
| 检测分子量 | |
| 性 状 | Liquid |
| 浓 度 | >1mg/ml |
| 纯 度 | >90% as determined by SDS-PAGE |
| 缓 冲 液 | 20mM Tris-Hcl (pH=8.0) with 4M Urea and 150mM NaCL |
| 保存条件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
Keratinocyte growth factor precursor (KGF) (Fibroblast growth factor 8; FGF-8; HBGF-8). Stimulates growth of the cells in an autocrine manner. Mediates hormonal action on the growth of cancer cells. Cooperates with Wnt-1 in mouse mammary tumor virus-induced murine mammary tumorigenesis. [Subcellular location] Secreted. [Tissue specificity] Absent in normal mammary glands and detected only in adult testis and ovary and in midgestational embryos. [Induction] By androgens. Belongs to the heparin-binding growth factors family. SWISS: P55075-3 Gene ID: 2253 有研究者认为：纤维母细胞生长因子8 FGF8 对癌症具有一定的抑制作用。 早期研究FGF8，认为是自分泌生长因子，它在前列腺癌、乳癌和卵巢癌中常常表现过量表达 (over-expressed)，并与前列腺癌的格里森分数 (Gleason score) 相关联。经过各种细胞和动物模型的实验均支持FGF8在抑制肿瘤形成和肿瘤细胞成活方面的作用。 此外，还有学者认为：FGF8 还在实验中显示出，他有改善因胶原蛋白引发的关节炎性的改变，如：风湿性关节炎和类风湿性关节炎及退行性骨性关节 |
| 产品图片 |
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
