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Recombinant human CD44 protein, C-His (HEK293) (bs-43776P)
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产品编号 bs-43776P
英文名称 Recombinant human CD44 protein, C-His (HEK293)
中文名称 重组人CD44蛋白
别    名 CD44_HUMAN; CD44 antigen; CDw44; Epican; Extracellular matrix receptor III; ECMR-III; GP90 lymphocyte homing/adhesion receptor; HUTCH-I; Heparan sulfate proteoglycan; Hermes antigen; Hyaluronate receptor; Phagocytic glycoprotein 1; PGP-1; Phagocytic glycoprotein I; PGP-I; LHR; MDU2; MDU3; MIC4; MC56; MIC4; Pgp1; CDW44; CSPG8; H-CAM; HCELL; ECM-III; HUTCH-1; Hermes-1;  
克 隆 号
理论分子量 24 kDa
检测分子量
性    状 Liquid
浓    度 >1mg/ml
纯    度 ≥ 90% as determined by SDS-PAGE.
缓 冲 液 PBS (pH=7.4)
保存条件 Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq, Jul 2008].

SWISS:
P16070

Gene ID:
960

CD44是一个重要的细胞表面粘附分子。它在许多类型的人类细胞上都表达,在很多生理和病理过程中有复杂的作用,例如细胞迁移和在肿瘤细胞的生长调控中。CD44传递着诸多的细胞通路,有研究者认为CD44是一个新的信号通路蛋白。CD44介导淋巴细胞与血管内皮细胞包括粘膜组织中高内皮小静脉的粘连,这可能是通过激活其它粘附分子而间接造成的。CD44也是肿瘤细胞浸润的重要因素。
产品图片
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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