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Recombinant mouse ADGRE1 protein, C-His (HEK293) (bs-43794P)
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说明书: 20ug  100ug  500ug
20ug/680.00元
100ug/2280.00元
500ug/6880.00元
大包装/询价

产品编号 bs-43794P
英文名称 Recombinant mouse ADGRE1 protein, C-His (HEK293)
中文名称 重组小鼠表皮生长因子样激素受体1蛋白
别    名 AGRE1_MOUSE; Adhesion G protein-coupled receptor E1; Emr1; Gpf480; Cell surface glycoprotein F4/80; EGF-like module receptor 1; EGF-like module-containing mucin-like hormone receptor-like 1; EMR1 hormone receptor; Ly71; F4/80; TM7LN3; DD7A5-7; EGF-TM7;  
克 隆 号
理论分子量 68.7 kDa
检测分子量
性    状 Liquid
浓    度 >1mg/ml
纯    度 ≥ 90% as determined by SDS-PAGE.
缓 冲 液 PBS (pH=7.4)
保存条件 Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 The epidermal growth factor (EGF)-TM7 family constitutes a group of class B G-protein coupled receptors, which includes CD97, EMR1 (EGF-like molecule containing mucin-like hormone receptor 1, designated F4/80 in mouse), EMR2, EMR3, FIRE, and ETL (1–3). These family members are characterized by an extended extracellular region with several N-terminal EGF domains, and are predominantly expressed on cells of the immune system (1–3). The EGF-TM7 protein family are encoded by a gene cluster on human chromosome 19p13 (1,3,4). The F4/80 molecule is solely expressed on the surface of macrophages and serves as a marker for mature macrophage tissues, including Kupffer cells in liver, splenic red pulp macrophages, brain microglia, gut lamina propria, and Langerhans cells in the skin (1). F4/80/EMR1 undergoes extensive N-linked glycosylation as well as some O-linked glycosylation (5,6). The function of F4/80/EMR1 is unclear, but it is speculated to be involved in macrophage adhesion events, cell migration, or as a G-protein coupled signaling component of macrophages.

SWISS:
Q61549

Gene ID:
13733

产品图片
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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