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Recombinant human FGF4 protein (Active,CHO) (bs-48099P)
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产品编号 bs-48099P
英文名称 Recombinant human FGF4 protein (Active,CHO)
中文名称 重组人成纤维细胞生长因子4
别    名 Fibroblast growth factor 4; FGF-4; Heparin secretory-transforming protein 1; HST; HST-1; HSTF-1; Heparin-binding growth factor 4; HBGF-4; Transforming protein KS3; FGF4; HST; HSTF1; KS3;  
理论分子量 19.3kDa
纯    度 ≥ 95% as determined by SDS-PAGE.
缓 冲 液 Lyophilized from a 0.22μm-filtered solution containing PBS, 5% mannitol and 0.01% Tween 80, pH7.4
保存条件 Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its oncogenic transforming activity. This gene and FGF3, another oncogenic growth factor, are located closely on chromosome 11. Co-amplification of both genes was found in various kinds of human tumors. Studies on the mouse homolog suggested a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway. [provided by RefSeq].

SWISS:
P08620

Gene ID:
2249

转录调节因子(Transcriptin Regulators) 纤维母细胞生长因子4是FGF家族的chengyu7成员。FGF家族参与一系列的生理功能:胚胎发育、细胞生长、器官形成、组织修复、肿瘤生长和侵袭。FGF3/FGF4在很多恶性肿瘤中呈高表达,被认为原癌基因之一。
产品图片
The purity of the protein is greater than 95% as determined by reducing SDS-PAGE.
Measured in a cell proliferation assay using NIH3T3 mouse embryonic fibroblast cells. The ED50 for this effect is 0.25-1 ng/mL
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