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Rabbit Anti-PRDM2/Biotin Conjugated antibody (bs-6062R-Bio)
~~~促销,代码KXJ230206-6~~~
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-6062R-Bio
英文名称 Anti-PRDM2/Biotin
中文名称 生物素标记的锌指蛋白RIZ1抗体
别    名 GATAGATA 3 binding protein G3B; GATA-3-binding protein G3B; HUMHOXY 1; HUMHOXY1; Lysine N methyltransferase 8; Lysine N-methyltransferase 8; MTB ZF; MTB-ZF; MTE binding protein; MTE-binding protein; PR domain containing 2 with ZNF domain; PR domain containing protein 2; PR domain zinc finger protein 2; PR domain-containing protein 2; PR-domain zinc finger protein 2; PRDM 2; PRDM2; PRDM2_HUMAN; Retinoblastoma protein binding zinc finger protein; Retinoblastoma protein interacting zinc- inger protein; retinoblastoma protein-interacting zinc finger protein; Retinoblastoma protein-interacting zinc-finger protein; RIZ 1; RIZ 2; RIZ; RIZ-LSB; RIZ1; RIZ2; Zinc finger DNA binding protein; Zinc finger protein RIZ.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  细胞生物  免疫学  神经生物学  信号转导  转录调节因子  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, )
产品应用 WB=1:50-200 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 189kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PRDM2/RIZ1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
S-adenosyl-L-methionine-dependent histone methyltransferase that specifically methylates 'Lys-9' of histone H3. May function as a DNA-binding transcription factor. Binds to the macrophage-specific TPA-responsive element (MTE) of the HMOX1 (heme oxygenase 1) gene and may act as a transcriptional activator of this gene.

Function:
S-adenosyl-L-methionine-dependent histone methyltransferase that specifically methylates 'Lys-9' of histone H3. May function as a DNA-binding transcription factor. Binds to the macrophage-specific TPA-responsive element (MTE) of the HMOX1 (heme oxygenase 1) gene and may act as a transcriptional activator of this gene.

Subunit:
Binds to the retinoblastoma protein (RB). Interacts with GATA3.

Subcellular Location:
Nucleus.

Tissue Specificity:
Highly expressed in retinoblastoma cell lines and in brain tumors. Also expressed in a number of other cell lines and in brain, heart, skeletal muscle, liver and spleen. Isoform 1 is expressed in testis at much higher level than isoform 3.

Similarity:
Contains 8 C2H2-type zinc fingers.
Contains 1 SET domain.

Database links:
UniProtKB/Swiss-Prot: Q13029.3

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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