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Rabbit Anti-Connexin-36/PE-Cy7 Conjugated antibody (bs-1266R-PE-Cy7)
~~~促销,代码KXJ230206-6~~~
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-1266R-PE-Cy7
英文名称 Anti-Connexin-36/PE-Cy7
中文名称 PE-Cy7标记的间隙连接蛋白36抗体
别    名 Connexin 36; CX36; Gap junction protein alpha 9; gap junction protein, alpha 9, 36kDa; GJA9; MGC138315; MGC138319; CXD2_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 神经生物学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Guinea Pig, )
产品应用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 36kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Connexin-36
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene encodes a member of the connexin protein family. Connexins are gap junction proteins which are arranged in groups of 6 around a central pore to form a connexon, a component of the gap junction intercellular channel. The channels formed by this protein allow cationic molecule exchange between human beta cells and may function in the regulation of insulin secretion. [provided by RefSeq, Oct 2012]

Function:
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.

Subunit:
A connexon is composed of a hexamer of connexins.

Subcellular Location:
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.

Tissue Specificity:
Highly expressed in neurons.

Similarity:
Highly expressed in neurons.
Belongs to the connexin family. Delta-type subfamily.

Database links:

Entrez Gene: 395273 Chicken

Entrez Gene: 282577 Cow

Entrez Gene: 57369 Human

Entrez Gene: 14617 Mouse

Entrez Gene: 50564 Rat

Entrez Gene: 378444 Zebrafish

Omim: 607058 Human

SwissProt: Q866T7 Cow

SwissProt: Q9UKL4 Human

SwissProt: O54851 Mouse

SwissProt: Q6PDP3 Mouse

SwissProt: O70610 Rat

Unigene: 283816 Human

Unigene: 389394 Mouse

Unigene: 9904 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

间隙连接是神经系统构成电突触的结构基础,参与调控神经冲动纤毫传递和复杂神经网络的整合,而Cx36是唯一一个在神经系统中优先表达的Cx,因此成为电生理研究主要蛋白。
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