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Rabbit Anti-AATK/Cy7 Conjugated antibody (bs-1510R-Cy7)
~~~促销,代码KXJ230206-6~~~
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-1510R-Cy7
英文名称 Anti-AATK/Cy7
中文名称 Cy7标记的AATK细胞凋亡关联酪氨酸激酶抗体
别    名 AATK; AATYK; AATYK1; Apoptosis associated tyrosine kinase; Apoptosis-associated tyrosine kinase; Brain apoptosis associated tyrosine kinase; Brain apoptosis-associated tyrosine kinase; CDK5 binding protein; CDK5-binding protein; KIAA0641; Lemur tyrosine kinase 1; LMR1; LMTK1; LMTK1_HUMAN; p35 binding protein; p35-binding protein; p35BP; Serine/threonine protein kinase LMTK1; Serine/threonine-protein kinase LMTK1.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  免疫学  神经生物学  信号转导  细胞凋亡  转录调节因子  激酶和磷酸酶  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, )
产品应用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 151kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human AATK
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
The protein encoded by this gene contains a tyrosine kinase domain at the N-terminus and a proline-rich domain at the C-terminus. This gene is induced during apoptosis, and expression of this gene may be a necessary pre-requisite for the induction of growth arrest and/or apoptosis of myeloid precursor cells. This gene has been shown to produce neuronal differentiation in a neuroblastoma cell line. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2011]

Function:
Apoptosis associated tyrosine kinase May be involved in neuronal differentiation.

Subunit:
Interacts with CDK5.

Subcellular Location:
Membrane; Single-pass type I membrane protein. Cytoplasm. Cytoplasm, perinuclear region.

Tissue Specificity:
Expressed in brain, and, to a lower extent, in kidney, heart, lung and skeletal muscle. Belongs to the protein kinase superfamily. Tyr protein kinase family.

Similarity:
Belongs to the protein kinase superfamily. Tyr protein kinase family.
Contains 1 protein kinase domain.

Database links:

Entrez Gene: 9625 Human

Omim: 605276 Human

SwissProt: Q6ZMQ8 Human

Unigene: 514575 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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