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Rabbit Anti-CNR1/Cy7 Conjugated antibody (bs-1683R-Cy7)
~~~促销,代码KXJ230206-6~~~
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-1683R-Cy7
英文名称 Anti-CNR1/Cy7
中文名称 Cy7标记的钙粘蛋白相关的神经受体1抗体
别    名 Cannabinoid Receptor I; CANN 6; CANN6; Cannabinoid receptor I brain; CB 1; CB R; CB1; CB1A; CB1K5; CbR; Central cannabinoid receptor; Central cannabinoid receptor isoform a; Central cannabinoid receptor isoform b; CNR 1; CNR; CNR-1; CNR1_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  免疫学  神经生物学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Rat,  (predicted: Mouse, Dog, Pig, Cow, Horse, Rabbit, Guinea Pig, )
产品应用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 52kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CNR-1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene. [provided by RefSeq, May 2009]

Function:
Involved in cannabinoid-induced CNS effects. Acts by inhibiting adenylate cyclase. Could be a receptor for anandamide. Inhibits L-type Ca(2+) channel current. Isoform 2 and isoform 3 have altered ligand binding.

Subunit:
Interacts (via C-terminus) with CNRIP1.

Subcellular Location:
Cell membrane.

Tissue Specificity:
Widely expressed.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

Database links:

Entrez Gene: 1268 Human

Entrez Gene: 12801 Mouse

Entrez Gene: 25248 Rat

Entrez Gene: 281087 Cow

Entrez Gene: 481913 Dog

Omim: 114610 Human

SwissProt: Q5IS73 Chimpanzee

SwissProt: P21554 Human

SwissProt: P47746 Mouse

SwissProt: P20272 Rat

Unigene: 709067 Human

Unigene: 75110 Human

Unigene: 7992 Mouse

Unigene: 222240 Rat

Unigene: 89774 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

CB1又称大麻素受体1,可导致大麻素类物质作用及代谢异常,从而影响胃肠动力及感觉.
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