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Rabbit Anti-FASTK/FITC Conjugated antibody (bs-1765R-FITC)
~~~促销,代码KXJ230206-6~~~
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-1765R-FITC
英文名称 Anti-FASTK/FITC
中文名称 FITC标记的Fas活化的丝/苏氨酸激酶抗体
别    名 FASTK; Fas-activated serine/threonine kinase; Fas activated serine threonine kinase; Fas activated serine threonine kinase isoform 1; Fas activated serine threonine kinase isoform 4; FAST; FAST kinase; FLJ13079.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  免疫学  信号转导  细胞凋亡  激酶和磷酸酶  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, )
产品应用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 60kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FAST kinase
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis promoting nuclear RNA binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full length natures have not yet been determined.

Subunit:
Interacts with TIA-1 and TIAR.

Tissue Specificity:
Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.

Similarity:
Belongs to the FAST protein kinase family.
Contains 1 RAP domain.

Database links:

Entrez Gene: 10922 Human

Entrez Gene: 66587 Mouse

Entrez Gene: 296741 Rat

Omim: 606965 Human

SwissProt: Q14296 Human

SwissProt: Q9JIX9 Mouse

Unigene: 647094 Human

Unigene: 28123 Mous



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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