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Rabbit Anti-Rad52/BF594 Conjugated antibody (bs-1878R-BF594)
~~~促销,代码KXJ230206-6~~~
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-1878R-BF594
英文名称 Anti-Rad52/BF594
中文名称 BF594标记的Rad52抗体
别    名 DNA repair protein RAD52; DNA repair protein RAD52 homolog; RAD 52; RAD52 homolog (S. cerevisiae); RAD52 homolog; Recombination protein RAD52; Rhabdomyosarcoma antigen MU RMS 40.23; DNA repair protein RAD52 homolog; RAD52_HUMAN; RAD52 homolog.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 染色质和核信号  转录调节因子  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 46kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Rad52
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
The protein encoded by this gene shares similarity with Saccharomyces cerevisiae Rad52, a protein important for DNA double-strand break repair and homologous recombination. This gene product was shown to bind single-stranded DNA ends, and mediate the DNA-DNA interaction necessary for the annealing of complementary DNA strands. It was also found to interact with DNA recombination protein RAD51, which suggested its role in RAD51 related DNA recombination and repair. [provided by RefSeq, Jul 2008]

Function:
Involved in double-stranded break repair. Plays a central role in genetic recombination and DNA repair by promoting the annealing of complementary single-stranded DNA and by stimulation of the RAD51 recombinase.

Subunit:
The full-length protein forms heptameric rings. Interacts with ABL1.

Subcellular Location:
Nucleus (Potential).

Post-translational modifications:
Phosphorylated upon DNA damage by ABL1, and probably by ATM or ATR.

Similarity:
Belongs to the RAD52 family.

Database links:

Entrez Gene: 5893 Human

Omim: 600392 Human

SwissProt: P43351 Human

Unigene: 410355 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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