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Rabbit Anti-RARRES1/Gold Conjugated antibody (bs-1916R-Gold)
~~~促销,代码KXJ230206-6~~~
订购热线:400-901-9800
订购邮箱:sales@bioss.com.cn
订购QQ:  400-901-9800
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说 明 书: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包装/询价
产品编号 bs-1916R-Gold
英文名称 Anti-RARRES1/Gold
中文名称 胶体金标记的视黄酸受体应答蛋白1抗体
别    名 Retinoic acid receptor responder protein 1; RAR-responsive protein TIG1; Tazarotene-induced gene 1 protein; TIG1_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul(10nm  15nm  35nm
研究领域 肿瘤  免疫学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Dog, Pig, Rabbit, )
产品应用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 33kDa
性    状 Lyophilized or Liquid
浓    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human RARRES1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存条件 Store at 2-8 ºC for 3-6 months. Avoid repeated freeze/thaw cycles.
产品介绍 background:
RARRES1 (Retinoic acid receptor responder 1) is a retinoid-regulated gene whose expression is down-regulated through DNA hypermethylation. It was originally identified as a target gene that was induced by the synthetic retinoid tazarotene (AGN 190168). Its expression is upregulated by retinoic acid receptor-specific, but not by retinoid X receptor-specific retinoids. Although the function of RARRES1 is not entirely clear, it is thought to act as a tumor suppressor of a variety of human cancers since inactivation of RARRES1 is involved in the malignant progression of prostate cancer. It may also function as a cell adhesion molecule. Additionally, RARRES1 may also have protease inhibitor activity and inhibit the degradation of extracellular matrix.

Subcellular Location:
Membrane; Single-pass type II membrane protein (Potential).

Similarity:
Belongs to the protease inhibitor I47 (latexin) family.

Database links:

Entrez Gene: 5918 Human

Omim: 605090 Human

SwissProt: P49788 Human

Unigene: 131269 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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