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Rabbit Anti-CD83/Gold Conjugated antibody (bs-2519R-Gold)
~~~促销,代码KXJ230206-6~~~
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说 明 书: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包装/询价
产品编号 bs-2519R-Gold
英文名称 Anti-CD83/Gold
中文名称 胶体金标记的CD83抗体
别    名 B cell activation 45kDa cell surface glycoprotein Ig superfamily; B cell activation protein; BL11; BL11 PEN; CD83 molecule; Cell surface protein HB15; HB15; MGC130312; MGC130313; Cell surface protein HB15; CD83_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul(10nm  15nm  35nm
研究领域 免疫学  细胞膜受体  t-淋巴细胞  b-淋巴细胞  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, )
产品应用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 21kDa
性    状 Lyophilized or Liquid
浓    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CD83
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存条件 Store at 2-8 ºC for 3-6 months. Avoid repeated freeze/thaw cycles.
产品介绍 background:
The CD83 antigen is a 186 amino acid single chain glycoprotein. This molecule is a member of the immunoglobulin superfamily and is composed of an extracellular V type immunoglobulin-like single domain, a transmembrane region, and a short, 40 amino acid cytoplasmic tail. CD83 antigen undergoes extensive post translational glycosylation, as the determined Mr is twice the predicted size of the core protein. However, CD83+ cells have a unique cell surface immunophenotype that does not correlate with that of T cells, B cells, NK cells, or cells of the myelomonocytic lineage. CD83+ cells coexpress the highest levels of MHC class II molecules, when compared with other leucocyte lineages. They also coexpress T cell markers (CD2, CD5), B cell markers (CD40, CD78), myeloid cell markers (CD13, CD33, CD36) and cytokine receptors, as well as other cell surface molecules.

Function:
May play a significant role in antigen presentation or the cellular interactions that follow lymphocyte activation (By similarity).

Subunit:
Monomer.

Subcellular Location:
Membrane; Single-pass type I membrane protein.

Tissue Specificity:
Abundantly expressed in spleen and brain, but is also detected in most tissues analyzed.

Similarity:
Contains 1 Ig-like V-type (immunoglobulin-like) domain.

Database links:

Entrez Gene: 9308 Human

Entrez Gene: 12522 Mouse

Entrez Gene: 361226 Rat

Omim: 604534 Human

SwissProt: Q01151 Human

SwissProt: O88324 Mouse

Unigene: 595133 Human

Unigene: 57175 Mouse

Unigene: 20096 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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