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Rabbit Anti-PPM2C/Gold Conjugated antibody (bs-3966R-Gold)
~~~促销,代码KXJ230206-6~~~
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订购QQ:  400-901-9800
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说 明 书: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包装/询价
产品编号 bs-3966R-Gold
英文名称 Anti-PPM2C/Gold
中文名称 胶体金标记的蛋白磷酸酶2C抗体
别    名 PDH; PDP 1; PDP; PDP1; PDPC 1; PDPC; Protein phosphatase 2C; protein phosphatase 2C, magnesium dependent, catalytic subunit; Pyruvate dehydrogenase phosphatase, catalytic subunit 1; PDP1_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul(10nm  15nm  35nm
研究领域 肿瘤  细胞生物  免疫学  信号转导  细胞凋亡  转录调节因子  激酶和磷酸酶  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, d)
产品应用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 52kDa
性    状 Lyophilized or Liquid
浓    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PPM2C
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存条件 Store at 2-8 ºC for 3-6 months. Avoid repeated freeze/thaw cycles.
产品介绍 background:
PPM2C is a protein similar to members of the protein phosphatase 2C (PP2C) family. It is a catalytic subunit of the mitochondrial matrix phosphatase and is involved in reactivation of the pyruvate dehydrogenase complex.

Function:
Catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex (By similarity).

Subunit:
Heterodimer of a catalytic (PDP1) and a regulatory (PDPR) subunit (By similarity).

Subcellular Location:
Mitochondrion matrix (By similarity).

DISEASE:
Defects in PDP1 are the cause of pyruvate dehydrogenase phosphatase deficiency (PDP deficiency) [MIM:608782]. PDP deficiency results in lactic acidosis leading to neurological dysfunction.

Similarity:
Belongs to the PP2C family.

Database links:
UniProtKB/Swiss-Prot: Q9P0J1.3

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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