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Rabbit Anti-ALDOB/PE-Cy7 Conjugated antibody (bs-4026R-PE-Cy7)
~~~促销,代码KXJ230206-6~~~
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-4026R-PE-Cy7
英文名称 Anti-ALDOB/PE-Cy7
中文名称 PE-Cy7标记的醛缩酶2抗体
别    名 ALDB; ALDO B; ALDO2; ALDOB; ALDOB_HUMAN; Aldolase 2; Aldolase B; Aldolase B fructose bisphosphate; Aldolase2; AldolaseB; EC 4.1.2.13; Fructose bisphosphate aldolase B; Fructose-bisphosphate aldolase B; Liver type aldolase; Liver-type aldolase; MS1077.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  细胞生物  免疫学  信号转导  转录调节因子  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human,  (predicted: Mouse, Rat, Pig, Cow, Rabbit, Sheep, )
产品应用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 39kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ALDOB
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
ALDOB is a tetrameric glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Defects in ALDOB cause hereditary fructose intolerance.

Subunit:
Homotetramer.

DISEASE:
Hereditary fructose intolerance (HFI) [MIM:229600]: Autosomal recessive disease that results in an inability to metabolize fructose and related sugars. Complete exclusion of fructose results in dramatic recovery; however, if not treated properly, HFI subjects suffer episodes of hypoglycemia, general ill condition, and risk of death the remainder of life. Note=The disease is caused by mutations affecting the gene represented in this entry.

Similarity:
Belongs to the class I fructose-bisphosphate aldolase family.

Database links:

Entrez Gene: 229 Human

Entrez Gene: 230163 Mouse

Entrez Gene: 24190 Rat

Omim: 612724 Human

SwissProt: P05062 Human

SwissProt: Q91Y97 Mouse

SwissProt: P00884 Rat

Unigene: 530274 Human

Unigene: 482116 Mouse

Unigene: 98207 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

醛缩酶(ALD)与机体能量代谢密切相关。醛缩酶含量比较丰富,分布也叫广泛,醛缩酶B是一种与糖酵解有关的酶类,在人类和哺乳动物组织中存在3种醛缩酶同工酶,即A(肌型),B(肝型)和C(脑型)。其中B型基因定位于q13-q32,属胞浆酶。研究表明,ALDOB在肝细胞癌发展过程中呈现出一定规律的变化,与原发性肝癌有关。ALDOB蛋白主要定位于胞浆。
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