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Rabbit Anti-CAPZA2/Cy3 Conjugated antibody (bs-5128R-Cy3)
~~~促销,代码KXJ230206-6~~~
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-5128R-Cy3
英文名称 Anti-CAPZA2/Cy3
中文名称 Cy3标记的F肌动蛋白α2亚基抗体
别    名 CAPPA2; CapZ alpha 2; Capping protein (actin filament) muscle Z line, alpha 2; CapZ alpha 2; CAPZ; F actin capping protein subunit alpha 2; CAZA2_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  免疫学  信号转导  转录调节因子  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep, )
产品应用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 33kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CapZ alpha 2
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
The protein encoded by this gene is a member of the F-actin capping protein alpha subunit family. It is the alpha subunit of the barbed-end actin binding protein Cap Z. By capping the barbed end of actin filaments, Cap Z regulates the growth of the actin filaments at the barbed end. [provided by RefSeq, Jul 2008]

Function:
F-actin-capping proteins bind in a Ca(2+)-independentmanner to the fast growing ends of actin filaments (barbed end)thereby blocking the exchange of subunits at these ends. Unlikeother capping proteins (such as gelsolin and severin), theseproteins do not sever actin filaments.

Subunit:
Heterodimer of an alpha and a beta subunit. Component ofthe WASH complex, composed of F-actin-capping protein subunit alpha(CAPZA1, CAPZA2 or CAPZA3), F-actin-capping protein subunit beta(CAPZB), WASH (WASH1, WASH2P, WASH3P, WASH4P, WASH5P or WASH6P),FAM21 (FAM21A, FAM21B or FAM21C), KIAA1033, KIAA0196 and CCDC53.Interacts with RCSD1/CAPZIP.

Similarity:
Belongs to the F-actin-capping protein alpha subunitfamily.

Database links:

Entrez Gene: 830 Human

Entrez Gene: 493728 Cow

Entrez Gene: 503863 Dog

Entrez Gene: 12343 Mouse

Entrez Gene: 493810 Rat

Omim: 601571 Human

SwissProt: Q5E997 Cow

SwissProt: A0M8V0 Dog

SwissProt: P47755 Human

SwissProt: P47754 Mouse

SwissProt: Q3T1K5 Rat

Unigene: 446123 Human

Unigene: 392504 Mouse

Unigene: 17868 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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