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Rabbit Anti-Gax/Gold Conjugated antibody (bs-1250R-Gold)
~~~促销,代码KXJ230206-6~~~
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说 明 书: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包装/询价
产品编号 bs-1250R-Gold
英文名称 Anti-Gax/Gold
中文名称 胶体金标记的生长终止特异性同源盒基因抗体
别    名 growth arrest-specific homeobox; Homeobox protein MOX-2; Mesenchyme homeobox 2; mesenchyme homeobox 2-like; Growth arrest-specific homeobox; GAX; growth arrest homeobox transcription factor GAX; mesenchyme homeobox 2; MEOX2_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul(10nm  15nm  35nm
研究领域 肿瘤  心血管  免疫学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, )
产品应用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 33kDa
性    状 Lyophilized or Liquid
浓    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Gax
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存条件 Store at 2-8 ºC for 3-6 months. Avoid repeated freeze/thaw cycles.
产品介绍 background:
This gene encodes a member of a subfamily of non-clustered, diverged, antennapedia-like homeobox-containing genes. The encoded protein may play a role in the regulation of vertebrate limb myogenesis. Mutations in the related mouse protein may be associated with craniofacial and/or skeletal abnormalities, in addition to neurovascular dysfunction observed in Alzheimers disease.

Function:
Role in mesoderm induction and its earliest regional specification, somitogenesis, and myogenic and sclerotomal differentiation. May have a regulatory role when quiescent vascular smooth muscle cells reenter the cell cycle (By similarity).

Subunit:
Interacts with RNF10.

Subcellular Location:
Nucleus. Nucleus speckle.

Similarity:
Contains 1 homeobox DNA-binding domain.

Database links:

Entrez Gene: 4223 Human

Entrez Gene: 17286 Mouse

Entrez Gene: 29279 Rat

Omim: 600535 Human

SwissProt: P50222 Human

SwissProt: P32443 Mouse

SwissProt: P39020 Rat

Unigene: 170355 Human

Unigene: 341398 Mouse

Unigene: 34890 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Gax主要在血管平滑肌细胞和内皮细胞中表达的同源异形盒基因,但Gax基因过表达可以抑制血管平滑肌细胞和内皮细胞的增殖,Gax也是脊椎动物肢体发育的重要调节因子,目前除用于心血管方面的研究,也用于肿瘤血管方面的探索。
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