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Rabbit Anti-PHAPI2/PE-Cy5.5 Conjugated antibody (bs-6769R-PE-Cy5.5)
~~~促销,代码KXJ230206-6~~~
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-6769R-PE-Cy5.5
英文名称 Anti-PHAPI2/PE-Cy5.5
中文名称 PE-Cy5.5标记的酸性核磷蛋白32家族B抗体
别    名 Acidic (leucine rich) nuclear phosphoprotein 32 family member B; Acidic leucine rich nuclear phosphoprotein 32 family member B; Acidic leucine-rich nuclear phosphoprotein 32 family member B; Acidic nuclear phosphoprotein 32 family member B; Acidic protein rich in leucines; AN32B_HUMAN; ANP 32B; ANP32B; APRIL; PAL 31; PAL31; PHAPI 2; PHAPI2; PHAPI2 protein; PHAPI2a; Proliferation related acidic leucine rich protein; Putative HLA-DR-associated protein I-2; Silver stainable protein SSP 29; Silver stainable protein SSP29; Silver-stainable protein SSP29; Ssp 29; Ssp29.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  信号转导  细胞凋亡  细胞周期蛋白  转录调节因子  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Dog, Cow, Fruit Fly, ,SheepDog,Zebrafish)
产品应用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 29kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from hu PHAPI2/APRIL
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Multifunctional protein working as a cell cycle progression factor as well as a cell survival factor. Required for the progression from the G1 to the S phase. Anti-apoptotic protein which functions as a caspase-3 inhibitor. Has no phosphatase 2A (PP2A) inhibitor activity (By similarity). Exhibits histone chaperone properties, stimulating core histones to assemble into a nucleosome.

Function:
Multifunctional protein working as a cell cycle progression factor as well as a cell survival factor. Required for the progression from the G1 to the S phase. Anti-apoptotic protein which functions as a caspase-3 inhibitor. Has no phosphatase 2A (PP2A) inhibitor activity (By similarity). Exhibits histone chaperone properties, stimulating core histones to assemble into a nucleosome.

Subunit:
Monomer. Interacts with histones H3 and H4.

Subcellular Location:
Isoform 1: Nucleus. Note=Accumulates in the nuclei at the S phase (By similarity).
Isoform 2: Cytoplasm. Note=Lacks a nuclear localization signal.

Tissue Specificity:
Expressed in heart, lung, pancreas, prostate and in spleen, thymus and placenta.

Post-translational modifications:
Some glutamate residues are glycylated by TTLL8. This modification occurs exclusively on glutamate residues and results in a glycine chain on the gamma-carboxyl group (By similarity).

Similarity:
Belongs to the ANP32 family.
Contains 4 LRR (leucine-rich) repeats.
Contains 1 LRRCT domain.

Database links:

Entrez Gene: 10541 Human

Entrez Gene: 67628 Mouse

Entrez Gene: 170724 Rat

SwissProt: Q92688 Human

SwissProt: Q9EST5 Mouse

SwissProt: Q9EST6 Rat

Unigene: 494604 Human

Unigene: 263913 Mouse

Unigene: 20465 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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