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Rabbit Anti-IEX1/PE-Cy5 Conjugated antibody (bs-6840R-PE-Cy5)
~~~促销,代码KXJ230206-6~~~
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订购邮箱:sales@bioss.com.cn
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-6840R-PE-Cy5
英文名称 Anti-IEX1/PE-Cy5
中文名称 PE-Cy5标记的分化相关基因2蛋白/立即早期反应蛋白抗体
别    名 IEX1; PRG1; Anti death protein; Differentiation dependent gene 2 protein; DIF 2; DIF2; Differentiation dependent gene 2; Differentiation dependent gene 2 protein; Differentiation-dependent gene 2 protein; Expressed in pancreatic carcinoma; GLY 96; GLY96; Gly96 mouse homolog of; IER 3; IER3; IEX 1; IEX 1L; IEX1_HUMAN; IEX1L; Immediate early protein GLY96; Immediate early response 3; Immediate early response 3 protein; Immediately early gene X 1; PACAP responsive gene 1; PACAP responsive gene 1 protein; PACAP-responsive gene 1 protein; PRG 1; Protein DIF 2; Protein DIF-2; Protein PRG1; Radiation-inducible immediate-early gene IEX-1.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  细胞生物  发育生物学  信号转导  干细胞  细胞凋亡  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 17kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human IEX1/Differentiation dependent gene 2 protein
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene functions in the protection of cells from Fas- or tumor necrosis factor type alpha-induced apoptosis. Partially degraded and unspliced transcripts are found after virus infection in vitro, but these transcripts are not found in vivo and do not generate a valid protein. [provided by RefSeq, Jul 2008].

Function:
May play a role in the ERK signaling pathway by inhibiting the dephosphorylation of ERK by phosphatase PP2A-PPP2R5C holoenzyme. Acts also as an ERK downstream effector mediating survival.

Subunit:
Interacts with the PPP2R5C-PP2A holoenzyme and ERK kinases; regulates ERK dephosphorylation.

Subcellular Location:
Membrane; Single-pass type II membrane protein.

Post-translational modifications:
Glycosylated.

Similarity:
Belongs to the IER3 family.

Database links:

Entrez Gene: 8870 Human

Entrez Gene: 15937 Mouse

Omim: 602996 Human

SwissProt: P46695 Human

SwissProt: P46694 Mouse

Unigene: 730861 Human

Unigene: 76095 Human

Unigene: 25613 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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