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Rabbit Anti-VDAC3/BF647 Conjugated antibody (bs-7647R-BF647)
~~~促销,代码KXJ230206-6~~~
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-7647R-BF647
英文名称 Anti-VDAC3/BF647
中文名称 BF647标记的线粒体外膜孔蛋白3/电压依赖阴离子通道蛋白3抗体
别    名 hVDAC3; mVDAC3; Outer mitochondrial membrane protein porin 3; voltage dependent anion channel 3; VDAC3_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  信号转导  细胞凋亡  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Rat,  (predicted: Human, Mouse, Dog, Pig, Cow, Horse, Rabbit, Sheep, DogZebrafish,Orangutan)
产品应用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 31kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human VDAC3
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene encodes a voltage-dependent anion channel (VDAC), and belongs to the mitochondrial porin family. VDACs are small, integral membrane proteins that traverse the outer mitochondrial membrane and conduct ATP and other small metabolites. They are known to bind several kinases of intermediary metabolism, thought to be involved in translocation of adenine nucleotides, and are hypothesized to form part of the mitochondrial permeability transition pore, which results in the release of cytochrome c at the onset of apoptotic cell death. Alternatively transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011]

Function:
Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules (By similarity).

Subcellular Location:
Mitochondrion outer membrane.

Tissue Specificity:
Widely expressed. Highest in testis.

Similarity:
Belongs to the eukaryotic mitochondrial porin family.

Database links:

Entrez Gene: 426793 Chicken

Entrez Gene: 282716 Cow

Entrez Gene: 7419 Human

Entrez Gene: 22335 Mouse

Entrez Gene: 83532 Rat

Omim: 610029 Human

SwissProt: Q9MZ13 Cow

SwissProt: Q9Y277 Human

SwissProt: Q60931 Mouse

SwissProt: Q9TT13 Rabbit

SwissProt: Q9R1Z0 Rat

Unigene: 699301 Human

Unigene: 227704 Mouse

Unigene: 107287 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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