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Rabbit Anti-FAM129B/Cy3 Conjugated antibody (bs-8205R-Cy3)
~~~促销,代码KXJ230206-6~~~
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-8205R-Cy3
英文名称 Anti-FAM129B/Cy3
中文名称 Cy3标记的FAM129B蛋白抗体
别    名 chromosome 9 open reading frame 88; DKFZP434H0820; FAM129B; family with sequence similarity 129, member B; FLJ13518; FLJ22151; FLJ22298; hypothetical protein LOC64855; Meg 3; Meg-3; Meg3; Niban like protein 1; Niban-like protein 1; NIBL1_HUMAN; OC58; Protein FAM129B; bA356B19.6; C9orf88.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  免疫学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Dog, Cow, Sheep, )
产品应用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 83kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FAM129B
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
May play a role in apoptosis suppression. May promote melanoma cell invasion in vitro.

Subcellular Location:
Cytoplasm, cytosol. Cell junction, adherens junction. Note=In exponentially growing cells, exclusively cytoplasmic. Cell membrane localization is observed when cells reach confluency and during telophase. In melanoma cells, targeting to the plasma membrane may be impaired by C-terminal phosphorylation.

Post-translational modifications:
Phosphorylated at Ser-641, Ser-646, Ser-692 and Ser-696 by the BRAF/MKK/ERK signaling cascade. In melanoma cells, the C-terminal phosphorylation may prevent targeting to the plasma membrane.
As apoptosis proceeds, degraded via an proteasome-independent pathway, probably by caspases (PubMed:21148485).

Similarity:
Belongs to the Niban family.
Contains 1 PH domain.

Database links:

Entrez Gene: 64855 Human

Entrez Gene: 227737 Mouse

SwissProt: Q96TA1 Human

SwissProt: Q8R1F1 Mouse

Unigene: 522401 Human

Unigene: 301646 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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