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Rabbit Anti-NAP1L1/PE-Cy3 Conjugated antibody (bs-1052R-PE-Cy3)
~~~促销,代码KXJ230206-6~~~
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-1052R-PE-Cy3
英文名称 Anti-NAP1L1/PE-Cy3
中文名称 PE-Cy3标记的核小体组装蛋白1抗体
别    名 NAP1L; FLJ16112; hNRP; HSP22 like protein interacting protein; MGC23410; MGC8688; NAP 1; NAP 1 related protein; NAP 1L; NAP-1 related protein; NAP-1-related protein; NAP1; NAP1 L1; NAP1 related protein; Nap1l1; NAP1L1 protein; NP1L1_HUMAN; NRP; Nucleosome assembly protein 1 like 1; Nucleosome assembly protein 1-like 1.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 染色质和核信号  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Rat,  (predicted: Mouse, )
产品应用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 44kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NAP1L1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene encodes a member of the nucleosome assembly protein (NAP) family. This protein participates in DNA replication and may play a role in modulating chromatin formation and contribute to the regulation of cell proliferation. The binding of sequence-specific DNA binding proteins to human nucleosome assembly protein 1 may be an important step contributing to the activation of transcription. May be involved in modulating chromatin formation and contribute to regulation of cell proliferation.

Function:
May be involved in modulating chromatin formation and contribute to regulation of cell proliferation.

Subcellular Location:
Nucleus. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

Tissue Specificity:
Ubiquitously expressed.

Post-translational modifications:
Polyglutamylated by TTLL4, a modification that occurs exclusively on glutamate residues and results in polyglutamate chains on the gamma-carboxyl group. Some residues may also be monoglycylated but not polyglycylated due to the absence of functional TTLL10 in human.

Similarity:
Belongs to the nucleosome assembly protein (NAP) family.

Database links:

Entrez Gene: 4673 Human

Entrez Gene: 53605 Mouse

Entrez Gene: 89825 Rat

Omim: 164060 Human

SwissProt: P55209 Human

SwissProt: P28656 Mouse

SwissProt: Q9Z2G8 Rat

Unigene: 524599 Human

Unigene: 695185 Human

Unigene: 290407 Mouse

Unigene: 162938 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

核小体组装蛋白1(NAP-1) 作为核心组蛋白的分子伴蛋白,在进化过程中是相当保守的.它通过帮助核心组蛋白沉积到DNA上来促进核小体的组装.而大量研究表明,酵母和动物中的NAP类似蛋白除了具有核小体组装能力以外,还有其它多种功能
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