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Rabbit Anti-PAPSS1/Cy5.5 Conjugated antibody (bs-9029R-Cy5.5)
~~~促销,代码KXJ230206-6~~~
订购热线:400-901-9800
订购邮箱:sales@bioss.com.cn
订购QQ:  400-901-9800
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-9029R-Cy5.5
英文名称 Anti-PAPSS1/Cy5.5
中文名称 Cy5.5标记的腺苷酸硫酸激酶1抗体
别    名 Adenylyl-sulfate kinase; Adenylylsulfate 3''-phosphotransferase; APS kinase; ATP-sulfurylase; ATPSK 1; ATPSK1; Bifunctional 3' phosphoadenosine 5' phosphosulfate synthetase 1; PAPS synthase 1; PAPS synthetase 1; PAPS1_HUMAN; PAPSS 1; PAPSS; PAPSS1; SAT; SK 1; SK1; Sulfate adenylate transferase; Sulfurylase kinase 1; 3 prime phosphoadenosine 5 prime phosphosulfate synthase 1; 3' phosphoadenosine 5' phosphosulfate synthase 1; 3''-phosphoadenosine-5''-phosphosulfate synthase; Adenosine-5''-phosphosulfate 3''-phosphotransferase.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  免疫学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, )
产品应用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 69kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PAPSS1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Three-prime-phosphoadenosine 5-prime-phosphosulfate (PAPS) is the sulfate donor cosubstrate for all sulfotransferase (SULT) enzymes (Xu et al., 2000 [PubMed 10679223]). SULTs catalyze the sulfate conjugation of many endogenous and exogenous compounds, including drugs and other xenobiotics. In humans, PAPS is synthesized from adenosine 5-prime triphosphate (ATP) and inorganic sulfate by 2 isoforms, PAPSS1 and PAPSS2 (MIM 603005).[supplied by OMIM, Mar 2008].

Function:
Bifunctional enzyme with both ATP sulfurylase and APS kinase activity, which mediates two steps in the sulfate activation pathway. The first step is the transfer of a sulfate group to ATP to yield adenosine 5'-phosphosulfate (APS), and the second step is the transfer of a phosphate group from ATP to APS yielding 3'-phosphoadenylylsulfate (PAPS: activated sulfate donor used by sulfotransferase). In mammals, PAPS is the sole source of sulfate; APS appears to be only an intermediate in the sulfate-activation pathway. Also involved in the biosynthesis of sulfated L-selectin ligands in endothelial cells.

Tissue Specificity:
Expressed in testis, pancreas, kidney, thymus, prostate, ovary, small intestine, colon, leukocytes and liver. Also expressed in high endothelial venules (HEV) cells and in cartilage.

Similarity:
In the N-terminal section; belongs to the APS kinase family.
In the C-terminal section; belongs to the sulfate adenylyltransferase family.

Database links:

Entrez Gene: 504439 Cow

Entrez Gene: 9060 Human

Entrez Gene: 9061 Human

Entrez Gene: 23971 Mouse

Entrez Gene: 295443 Rat

Omim: 603262 Human

SwissProt: O43252 Human

SwissProt: O95340 Human

SwissProt: O88428 Mouse

SwissProt: Q60967 Mouse

Unigene: 368610 Human

Unigene: 524491 Human

Unigene: 203916 Mouse

Unigene: 244912 Mouse

Unigene: 3507 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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