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Rabbit Anti-SP-B/Surfactant Protein B/BF647 Conjugated antibody (bs-1034R-BF647)
~~~促销,代码KXJ230206-6~~~
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-1034R-BF647
英文名称 Anti-SP-B/Surfactant Protein B/BF647
中文名称 BF647标记的肺表面活性蛋白B抗体
别    名 18 kDa pulmonary surfactant protein; 18 kDa pulmonary-surfactant protein; 6 kDa protein; Pulmonary surfactant apoprotein PSP B; Pulmonary surfactant associated protein B 18kD; Pulmonary surfactant associated protein B; Pulmonary surfactant associated proteolipid SPL Phe; SFTB3; SFTP3; SFTPB; SFTPB surfactant; Surfactant pulmonary associated protein B; Prosurfactant Protein B; pulmonary surfactant-associated glycoprotein B; proSP B; PSP B; PSPB; PSPB_MOUSE; Pulmonary surfactant-associated protein B; Pulmonary surfactant-associated proteolipid SPL(Phe); SFTB3; SFTP3; SFTPB; SP B; SP-B; SPB.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  心血管  信号转导  新陈代谢  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Rat,  (predicted: Mouse, )
产品应用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 9kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from mouse SP-B
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Pulmonary surfactant-associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces. SP-B increases the collapse pressure of palmitic acid to nearly 70 millinewtons per meter.Homodimer; disulfide-linked. Secreted, extracellular space.

Function:
Pulmonary surfactant-associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces. SP-B increases the collapse pressure of palmitic acid to nearly 70 millinewtons per meter.

Subunit:
Homodimer; disulfide-linked.

Subcellular Location:
Secreted, extracellular space, surface film.

Similarity:
Contains 1 saposin A-type domain.
Contains 3 saposin B-type domains.

Database links:

Entrez Gene: 6439 Human

Entrez Gene: 20388 Mouse

Omim: 178640 Human

SwissProt: P15781 Cow

SwissProt: P07988 Human

SwissProt: P50405 Mouse

Unigene: 512690 Human

Unigene: 46033 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

肺泡表面活性物质B(SP-B)也属糖结合蛋白家族,参与肺泡表面活性膜的形成和代谢,除在Ⅱ型细胞中强烈表达外,在细支气管、支气管上皮内也有灶性表达。SP-B是疏水性蛋白,主要效应是促进磷脂吸附和分布到肺泡气-液交界面,促进磷脂单分子层的形成,只有这种单分子层磷脂才能使表面张力降低到最低水平。
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