| 产品编号 | bs-0625R-Gold |
| 英文名称 | Anti-ZNF268/Gold |
| 中文名称 | 胶体金标记的锌指脂蛋白抗体 |
| 别 名 | zinc finger protein ZNF268; zinc finger protein 268 isoform c; zinc finger protein 3; zinc finger protein HZF3; HZF3; MGC126498; ZN268_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul（10nm 15nm 35nm） |
| 研究领域 | 染色质和核信号 信号转导 转录调节因子 结合蛋白 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | (predicted: Human, ) |
| 产品应用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 108kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 0.4mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ZNF268 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
| 保存条件 | Store at 2-8 ºC for 3-6 months. Avoid repeated freeze/thaw cycles. |
| 产品介绍 |
background: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a krueppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. Zinc finger protein 268 (ZNF268), also known as zinc finger protein 3 or HZF3, is a 947 amino acid protein belonging to the krueppel C2H2-type zinc-finger protein family. ZNF268 contains 24 C2H2-type zinc fingers and one KRAB domain. Localized to the nucleus, ZNF268 is involved in transcriptional regulation and is highly expressed in three to five week old embryos. ZNF268 has been implicated in human leukemia, due to the identification of an alternatively spliced form in leukemia patients. Two named isoforms of ZNF268 exist as a result of alternative splicing events. Function: May be involved in transcriptional regulation. Subcellular Location: Nucleus (Probable). Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family. Contains 24 C2H2-type zinc fingers. Contains 1 KRAB domain. Database links: Entrez Gene: 10795 Human Omim: 604753 Human SwissProt: Q14587 Human Unigene: 124047 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 锌指基因家族是人体中最大的基因家族，它参与细胞分化、胚胎发育，并与许多疾病的发生相关。 人类ZNF268基因是一个在人胚肝中特异性表达的C2H2型锌指基因，并可能在人的早期肝脏发育中起重要作用. |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
