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Rabbit Anti-ABAT/APC Conjugated antibody (bs-4234R-APC)
~~~促销,代码KXJ230206-6~~~
订购热线:400-901-9800
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-4234R-APC
英文名称 Anti-ABAT/APC
中文名称 APC标记的γ氨基丁酸转氨酶抗体
别    名 mitochondrial; (S) 3 amino 2 methylpropionate transaminase; (S)-3-amino-2-methylpropionate transaminase; 4 aminobutyrate aminotransferase; 4 aminobutyrate aminotransferase, mitochondrial; 4-aminobutyrate aminotransferase; ABAT; GABA aminotransferase; GABA AT; GABA T; GABA transaminase; GABA transferase; GABA-AT; GABA-T; GABAT; GABT_HUMAN; Gamma amino N butyrate transaminase; Gamma-amino-N-butyrate transaminase; L AIBAT; L-AIBAT; LAIBAT.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  免疫学  神经生物学  信号转导  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Rat,  (predicted: Human, Mouse, Pig, Cow, Horse, )
产品应用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 56kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ABAT
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Catalyzes the conversion of gamma-aminobutyrate and L-beta-aminoisobutyrate to succinate semialdehyde and methylmalonate semialdehyde, respectively. Can also convert delta-aminovalerate and beta-alanine.

Function:
Catalyzes the conversion of gamma-aminobutyrate and L-beta-aminoisobutyrate to succinate semialdehyde and methylmalonate semialdehyde, respectively. Can also convert delta-aminovalerate and beta-alanine.

Subunit:
Homodimer; disulfide-linked.

Subcellular Location:
Mitochondrion matrix.

Tissue Specificity:
Liver > pancreas > brain > kidney > heart > placenta.

DISEASE:
Defects in ABAT are a cause of gamma-aminobutyrate transaminase deficiency (GABA-AT deficiency) [MIM:613163]. The phenotype of this deficiency includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities.

Similarity:
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

Database links:

Entrez Gene: 18 Human

Entrez Gene: 268860 Mouse

Entrez Gene: 81632 Rat

Omim: 137150 Human

SwissProt: P80404 Human

SwissProt: P61922 Mouse

SwissProt: P50554 Rat

Unigene: 336768 Human

Unigene: 259315 Mouse

Unigene: 10090 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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