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Rabbit Anti-ANKHD1/RBITC Conjugated antibody (bs-5831R-RBITC)
~~~促销,代码KXJ230206-6~~~
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-5831R-RBITC
英文名称 Anti-ANKHD1/RBITC
中文名称 罗丹明(RBITC)标记的艾滋病病毒制约锚定蛋白抗体
别    名 ANKH1_HUMAN; ANKHD 1; ANKHD1; Ankyrin repeat and KH domain containing 1; Ankyrin repeat and KH domain containing protein 1; Ankyrin repeat and KH domain-containing protein 1; HIV-1 Vpr-binding ankyrin repeat protein; HIV1 Vpr binding ankyrin repeat protein; hMASK; MASK; Multiple ankyrin repeats single KH domain; Multiple ankyrin repeats single KH domain homolog; VBARP.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  细胞生物  免疫学  细菌及病毒  细胞粘附分子  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Dog, Pig, Cow, Horse, Sheep, )
产品应用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 269kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ANKHD1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
May play a role as a scaffolding protein that may be associated with the abnormal phenotype of leukemia cells. Isoform 2 may possess an antiapoptotic effect and protect cells during normal cell survival through its regulation of caspases.

Function:
May play a role as a scaffolding protein that may be associated with the abnormal phenotype of leukemia cells. Isoform 2 may possess an antiapoptotic effect and protect cells during normal cell survival through its regulation of caspases.

Subunit:
Interacts with PTPN11. Isoform 2 interacts with HIV-1 VPR.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Ubiquitous with high expression in cervix, spleen and brain. Expressed in hematopoietic cells with increased expression in leukemia cells. Isoform 2 is highly expressed in spleen with almost no expression in muscle and brain.

Similarity:
Belongs to the mask family.
Contains 25 ANK repeats.
Contains 1 KH domain.

Database links:

Entrez Gene: 54882 Human

Omim: 610500 Human

SwissProt: Q8IWZ3 Human

Unigene: 594084 Human

Unigene: 720987 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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