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Rabbit Anti-SLC35C2/PE-Cy3 Conjugated antibody (bs-12118R-PE-Cy3)
~~~促销,代码KXJ230206-6~~~
订购热线:400-901-9800
订购邮箱:sales@bioss.com.cn
订购QQ:  400-901-9800
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-12118R-PE-Cy3
英文名称 Anti-SLC35C2/PE-Cy3
中文名称 PE-Cy3标记的溶质载体蛋白家族35成员C2抗体
别    名 BA394O2.1; C20orf5; CGI-15; FLJ37039; MGC20633; MGC32079; MGC39183; Ovarian cancer-overexpressed gene 1 protein; OVCOV1; S35C2_HUMAN; SLC35C2; Solute carrier family 35 member C2.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  心血管  细胞生物  神经生物学  信号转导  新陈代谢  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human,  (predicted: Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit, Sheep, )
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 40kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SLC35C2
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
SLC35C2 (solute carrier family 35, member C2), also known as C20orf5, OVCOV1 or CGI-15, is a 365 amino acid multi-pass membrane protein that belongs to the TPT transporter family and exists as multiple alternatively spliced isoforms. Expressed ubiquitously and functionally induced in hypoxic trophoblast cells, SLC35C2 plays a role in the cellular response to tissue hypoxia and is thought to be involved in the pathogenesis of ovarian cancer. The gene encoding SLC35C2 maps to human chromosome 20, which houses over 600 genes some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome. Additionally, chromosome 20 contains a region with numerous genes which are thought important for seminal production and may be potential targets for male contraception.

Function:
May play an important role in the cellular response to tissue hypoxia.

Subcellular Location:
Membrane.

Tissue Specificity:
Ubiquitously expressed although the level of expression is tissue dependent. Overexpressed in ovarian cancer.

Similarity:
Belongs to the TPT transporter family. SLC35C subfamily.

Database links:

Entrez Gene: 514485 Cow

Entrez Gene: 609863 Dog

Entrez Gene: 100056733 Horse

Entrez Gene: 51006 Human

Entrez Gene: 228875 Mouse

Entrez Gene: 100152375 Pig

Entrez Gene: 100349356 Rabbit

Entrez Gene: 311637 Rat

Entrez Gene: 323482 Zebrafish

SwissProt: Q9NQQ7 Human

SwissProt: Q8VCX2 Mouse

Unigene: 593344 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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