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Rabbit Anti-CGBP/RBITC Conjugated antibody (bs-13878R-RBITC)
~~~促销,代码KXJ230206-6~~~
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-13878R-RBITC
英文名称 Anti-CGBP/RBITC
中文名称 罗丹明(RBITC)标记的CpG结合蛋白抗体
别    名 2410002I16Rik; 5830420C16Rik; AI426635; CFP 1; CFP1; CpG binding protein; CpG-binding protein; CXXC 1; CXXC finger 1; CXXC finger 1 PHD domain; CXXC finger protein 1; CXXC type zinc finger protein 1; CXXC-type zinc finger protein 1; CXXC1; CXXC1_HUMAN; DNA binding protein with PHD finger and CXXC domain; hCGBP; HsT2645; PCCX 1; PCCX1; PHD finger and CXXC domain containing protein 1; PHD finger and CXXC domain-containing protein 1; PHF 18; PHF18; Protein containing CXXC domain 1; SPP 1; SPP1; ZCGPC 1; ZCGPC1; Zinc finger, CpG binding type containing 1.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  转录调节因子  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, )
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 56kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CGBP
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Proteins that contain a CXXC motif within their DNA-binding domain, such as CXXC1, recognize CpG sequences and regulate gene expression (Carlone and Skalnik, 2001 [PubMed 11604496]).[supplied by OMIM, Mar 2008]

Function:
Transcriptional activator that exhibits a unique DNA binding specificity for [AC]CpG[AC] unmethylated CpG motifs.

Subcellular Location:
Nucleus speckle. Associated with euchromatin. During mitosis, excluded from condensed chromosomes.

Tissue Specificity:
Ubiquitous.

Post-translational modifications:
May be regulated by proteolysis.

Similarity:
Contains 1 CXXC-type zinc finger.
Contains 1 PHD-type zinc finger.

Database links:

Entrez Gene: 30827 Human

Entrez Gene: 74322 Mouse

Entrez Gene: 291440 Rat

Omim: 609150 Human

SwissProt: Q9P0U4 Human

SwissProt: Q9CWW7 Mouse

SwissProt: A1A5S2 Rat

Unigene: 180933 Human

Unigene: 17537 Mouse

Unigene: 86349 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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