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Rabbit Anti-CYC1/Gold Conjugated antibody (bs-14135R-Gold)
~~~促销,代码KXJ230206-6~~~
订购热线:400-901-9800
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说 明 书: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包装/询价
产品编号 bs-14135R-Gold
英文名称 Anti-CYC1/Gold
中文名称 胶体金标记的细胞色素C1抗体
别    名 Complex III subunit 4; Complex III subunit IV; CY1_HUMAN; CYC1; Cytochrome b c1 complex subunit 4; Cytochrome b-c1 complex subunit 4; Cytochrome bc1 complex subunit 4; Cytochrome c 1; Cytochrome c-1; Cytochrome c1, heme protein, mitochondrial; Ubiquinol cytochrome c reductase complex cytochrome c1 subunit; Ubiquinol-cytochrome-c reductase complex cytochrome c1 subunit; UQCR4.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul(10nm  15nm  35nm
研究领域 细胞生物  信号转导  转录调节因子  细胞类型标志物  新陈代谢  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Pig, Cow, Monkey, )
产品应用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 27kDa
性    状 Lyophilized or Liquid
浓    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CYC1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存条件 Store at 2-8 ºC for 3-6 months. Avoid repeated freeze/thaw cycles.
产品介绍 background:
Cytochrome c1 is a component of the ubiquinol-cytochrome c reductase complex, which is a respiratory chain that generates an electrochemical potential, coupled to ATP synthesis. Specifically, cytochrome c transfers electrons from the cytochrome bc1 complex to cytochrome c oxidase by transiently binding to the complex. The bc1 complex contains 11 subunits: 3 respiratory subunits (cytochrome b, cytochrome c1 and Rieske/UQCRFS1), 2 core proteins (UQCRC1/QCR1 and UQCRC2/QCR2) and 6 low-molecular weight proteins (UQCRH/QCR6, UQCRB/QCR7, UQCRQ/QCR8, UQCR10/QCR9, UQCR11/QCR10 and a cleavage product of Rieske/UQCRFS1). Cytochrome c1 binds one heme per subunit as a result of a mutation-induced collapse of the di-heme cytochrome structure. The cytochrome c1 gene is thought to be regulated by E2F and Sp1 transcription factors.

Function:
This is the heme-containing component of the cytochrome b-c1 complex, which accepts electrons from Rieske protein and transfers electrons to cytochrome c in the mitochondrial respiratory chain.

Subcellular Location:
Mitochondrion inner membrane.

Post-translational modifications:
Binds 1 heme group per subunit.

Similarity:
Belongs to the cytochrome c family.
Contains 1 cytochrome c domain.

Database links:

Entrez Gene: 1537 Human

Entrez Gene: 512500 Cow

Entrez Gene: 66445 Mouse

Omim: 123980 Human

SwissProt: P00125 Cow

SwissProt: P08574 Human

SwissProt: Q9D0M3 Mouse

Unigene: 1808 Cow

Unigene: 289271 Human

Unigene: 29196 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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