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Rabbit Anti-TXLNB/BF488 Conjugated antibody (bs-12153R-BF488)
~~~促销,代码KXJ230206-6~~~
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-12153R-BF488
英文名称 Anti-TXLNB/BF488
中文名称 BF488标记的β-taxilin蛋白抗体
别    名 Beta-taxilin; C6orf198; dJ522B19.2; DKFZp451A175; hMDP77; LST001; MDP77; Muscle-derived protein 77; RP3-522B19.2; Txlnb; TXLNB_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 神经生物学  信号转导  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, )
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 76kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TXLNB
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Beta-taxilin promotes nerve regeneration and may be involved in intracellular vesicle transport. Expressed predominantly in cardiac and skeletal muscle, beta-taxilin binds to the coiled coil region of the syntaxin family members STX1A, STX3A, and STX4A. Beta- and gamma-taxilins, bind to the alpha subunit of the nascent polypeptide-associated complex (NAC) and affect its nuclear distribution, suggesting that the taxilin family is involved not only in the translational process through its interaction with NAC but also in the transcriptional process through its interaction with alphaNAC alone.

Function:
Promotes motor nerve regeneration (By similarity). May be involved in intracellular vesicle traffic.

Subunit:
Binds to the C-terminal coiled coil region of syntaxin family members STX1A, STX3A and STX4A. Has a preference for STX1A.

Tissue Specificity:
Expressed in skeletal muscle.

Similarity:
Belongs to the taxilin family.

Database links:

Entrez Gene: 167838 Human

Entrez Gene: 378431 Mouse

Entrez Gene: 308622 Rat

Omim: 611438 Human

SwissProt: Q8N3L3 Human

SwissProt: Q8VBT1 Mouse

Unigene: 535820 Human

Unigene: 283493 Mouse

Unigene: 165855 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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