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Rabbit Anti-C1orf69/AP Conjugated antibody (bs-15075R-AP)
~~~促销,代码KXJ230206-6~~~
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-15075R-AP
英文名称 Anti-C1orf69/AP
中文名称 碱性磷酸酶(AP)标记的1号染色体开放阅读框69抗体
别    名 C1orf69; CA069_HUMAN; CAF17_HUMAN; FLJ12734; FLJ13849; IBA57; IBA57 iron sulfur cluster assembly homolog; IBA57 iron sulfur cluster assembly homolog (S. cerevisiae); Iron sulfur cluster assembly factor for biotin synthase and aconitase like; Iron-sulfur cluster assembly factor homolog; mitochondrial; Mitochondrial proteins with a mass of 57kDa; Putative transferase C1orf69; Putative transferase C1orf69 mitochondrial; Putative transferase CAF17, mitochondrial.   
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  免疫学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Pig, )
产品应用 WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 34kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human C1orf69
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Belonging to the CAF17 subfamily of the gcvT family, C1orf69 is a 356 amino acid mitochondrial protein that is required for normal heme synthesis. Heme synthesis is dependent upon receiving iron through iron sulfur (Fe-S) cluster biogenesis proteins such as C1orf69, which is specifically thought to assemble Fe-S clusters for mitochondrial aconitase and lipoate synthase. In zebrafish, deficiency of C1orf69 causes anemia. The gene encoding C1orf69 maps to human chromosome 1, the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1.

Function:
Required for normal heme biosynthesis (By similarity).

Subcellular Location:
Mitochondrion (Potential).

Similarity:
Belongs to the GcvT family. CAF17 subfamily.

Database links:
UniProtKB/Swiss-Prot: Q5T440.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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