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Rabbit Anti-eEF1A2/Cy7 Conjugated antibody (bs-13054R-Cy7)
~~~促销,代码KXJ230206-6~~~
订购热线:400-901-9800
订购邮箱:sales@bioss.com.cn
订购QQ:  400-901-9800
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-13054R-Cy7
英文名称 Anti-eEF1A2/Cy7
中文名称 Cy7标记的翻译延伸因子EF-1 α2抗体
别    名 eEF1A 2; eEF1A-2; Eef1a2; EEF1AL; EF 1 alpha 2; EF-1-alpha-2; EF1A; EF1A2_HUMAN; Elongation factor 1 A 2; Elongation factor 1 alpha; Elongation factor 1 alpha 2; Elongation factor 1-alpha 2; Eukaryotic elongation factor 1 A-2; Eukaryotic translation elongation factor 1 alpha 2; HS1; OTTHUMP00000031776; Statin like; Statin S1; Statin-S1; STN; STNL.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  心血管  细胞生物  神经生物学  转录调节因子  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Mouse,  (predicted: Human, Rat, Zebrafish, )
产品应用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 50kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human eEF1A2
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Elongation factor 1 alpha 2 (EF-1 alpha2) is a eukaryotic protein translation factor that is expressed in terminally differentiated cells of skeletal muscle, heart, and certain areas of the brain. Along with protein synthesis, EF-1 alpha2 also plays a role in cytoskeletal remodelling and apoptosis. The gene encoding for EF-1 alpha2 maps to chromosome 20q13. Wasted (wst) refers to a spontaneous autosomal recessive mutation in which this gene is deleted, and it leads to tremors and disturbances of gait shortly after weaning, followed by motor neuron degeneration, paralysis, and death by about 28 days in mice. EF-1 alpha2 has the ability to transform mammalian cells and is highly expressed in tumors of the ovary, breast, and lung, thereby proving a good candidate for an oncogene. In addition to this, EF-1 alpha2 enhances focus formation, allows anchorage-independent growth, and decreases the doubling time of rodent fibroblasts.

Function:
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

Subunit:
Monomer

Subcellular Location:
Nucleus.

Tissue Specificity:
Brain, heart, and skeletal muscle.

Similarity:
Belongs to the GTP-binding elongation factor family. EF-Tu/EF-1A subfamily.

Database links:

Entrez Gene: 1917 Human

Entrez Gene: 13628 Mouse

Entrez Gene: 24799 Rat

Entrez Gene: 101109898 Sheep

Entrez Gene: 380550 Xenopus laevis

Omim: 602959 Human

SwissProt: Q05639 Human

SwissProt: P62631 Mouse

SwissProt: P62632 Rat

Unigene: 433839 Human

Unigene: 2645 Mouse

Unigene: 9764 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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