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Rabbit Anti-ARPC4/BF488 Conjugated antibody (bs-12528R-BF488)
~~~促销,代码KXJ230206-6~~~
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-12528R-BF488
英文名称 Anti-ARPC4/BF488
中文名称 BF488标记的肌动蛋白相关蛋白2/3亚型4抗体
别    名 Actin related protein 2/3 complex subunit 4; Actin related protein 2/3 complex subunit 4 20 kD; Actin related protein 2/3 complex subunit 4 20kDa; Actin-related protein 2/3 complex subunit 4; ARC20; Arp2/3 complex 20 kDa subunit; Arp2/3 protein complex subunit p20; ARPC 4; ARPC4; ARPC4_HUMAN; MGC13544; OTTHUMP00000165252; OTTHUMP00000207520; p20 Arc; p20-ARC; p20ARC.   
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  信号转导  结合蛋白  细胞骨架  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Chicken, Cow, Rabbit, Zebrafish, Sheep, Xenopus laevis)
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 20kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ARPC4/p20-ARC
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene encodes one of seven subunits of the human Arp2/3 protein complex. This complex controls actin polymerization in cells and has been conserved throughout eukaryotic evolution. This gene encodes the p20 subunit, which is necessary for actin nucleation and high-affinity binding to F-actin. Alternative splicing results in multiple transcript variants. Naturally occurring read-through transcription exists between this gene and the downstream tubulin tyrosine ligase-like family, member 3 (TTLL3), which results in the production of a fusion protein. [provided by RefSeq, Nov 2010].

Function:
Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament.

Subunit:
Component of the Arp2/3 complex composed of ARP2, ARP3, ARPC1B/p41-ARC, ARPC2/p34-ARC, ARPC3/p21-ARC, ARPC4/p20-ARC and ARPC5/p16-ARC.

Subcellular Location:
Cytoplasm; cytoskeleton. Cell projection.

Similarity:
Belongs to the ARPC4 family.

Database links:

Entrez Gene: 10093 Human

Entrez Gene: 68089 Mouse

Entrez Gene: 539459 Cow

Entrez Gene: 100155875 Pig

Entrez Gene: 297518 Rat

Entrez Gene: 114456 Zebrafish

Omim: 604226 Human

SwissProt: Q148J6 Cow

SwissProt: P59998 Human

SwissProt: P59999 Mouse

Unigene: 323342 Human

Unigene: 289306 Mouse

Unigene: 472172 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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