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Rabbit Anti-FPGS/Gold Conjugated antibody (bs-13196R-Gold)
~~~促销,代码KXJ230206-6~~~
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说 明 书: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包装/询价
产品编号 bs-13196R-Gold
英文名称 Anti-FPGS/Gold
中文名称 胶体金标记的叶酸盐多谷氨酸合成酶抗体
别    名 EC 6.3.2.17; FOLC; FOLC_HUMAN; Folylpoly gamma glutamate synthetase; Folylpoly-gamma-glutamate synthetase; Folylpolyglutamate synthase; Folylpolyglutamate synthase mitochondrial; FPGS; mitochondrial; OTTHUMP00000022201; OTTHUMP00000022202; Tetrahydrofolate synthase; Tetrahydrofolylpolyglutamate synthase.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul(10nm  15nm  35nm
研究领域 肿瘤  细胞生物  信号转导  新陈代谢  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Dog, Horse, Rabbit, )
产品应用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 60kDa
性    状 Lyophilized or Liquid
浓    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FPGS/Folylpolyglutamate synthase
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存条件 Store at 2-8 ºC for 3-6 months. Avoid repeated freeze/thaw cycles.
产品介绍 background:
This gene encodes the folylpolyglutamate synthetase enzyme. This enzyme has a central role in establishing and maintaining both cytosolic and mitochondrial folylpolyglutamate concentrations and, therefore, is essential for folate homeostasis and the survival of proliferating cells. This enzyme catalyzes the ATP-dependent addition of glutamate moieties to folate and folate derivatives. While several transcript variants may exist for this gene, the full-length natures of only two have been biologically validated to date. These two variants encode distinct isoforms. [provided by RefSeq, Jul 2008].

Function:
Conversion of folates to polyglutamate derivatives. This allows tissues to concentrate folate at higher levels than in plasma.

Subunit:
Monomer.

Subcellular Location:
Mitochondrion. Cytoplasm.

Similarity:
Belongs to the folylpolyglutamate synthase family.

Database links:

Entrez Gene: 2356 Human

Omim: 136510 Human

SwissProt: Q05932 Human

Unigene: 335084 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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