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Rabbit Anti-DNA Polymerase epsilon/Cy5.5 Conjugated antibody (bs-14355R-Cy5.5)
~~~促销,代码KXJ230206-6~~~
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-14355R-Cy5.5
英文名称 Anti-DNA Polymerase epsilon/Cy5.5
中文名称 Cy5.5标记的DNA聚合酶ε/DNA pol ε抗体
别    名 Arsenic transactivated protein; Arsenic-transactivated protein; ASTP; CHARAC 17; CHARAC17; CHRAC 17; CHRAC-17; CHRAC17; Chromatin Accessibility Complex 17; Chromatin accessibility complex 17 kDa protein; DNA Polymerase Epsilon p17 Subunit; DNA polymerase epsilon subunit 3; DNA polymerase epsilon subunit p17; DNA polymerase II subunit 3; DPOE3_HUMAN; Histone fold protein CHRAC17; HuCHRAC 17; HuCHRAC17; p17; p17 subunit; POL E3; POLE 3; POLE3; Polymerase (DNA directed) epsilon 3; YBL 1;   
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  转录调节因子  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, )
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 16kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DNA Polymerase epsilon
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
OLE3 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers combine within larger enzymatic complexes for DNA transcription, replication, and packaging.[supplied by OMIM, Apr 2004]

Function:
Forms a complex with DNA polymerase epsilon subunit CHRAC1 and binds naked DNA, which is then incorporated into chromatin, aided by the nucleosome-remodeling activity of ISWI/SNF2H and ACF1.

Subcellular Location:
Nucleus.

Tissue Specificity:
Expressed in all tissues tested, including, heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.

Database links:

Entrez Gene: 54107 Human

Entrez Gene: 417275 Chicken

Entrez Gene: 510678 Cow

Entrez Gene: 59001 Mouse

Entrez Gene: 100362333 Rat

Entrez Gene: 298098 Rat

Omim: 607267 Human

SwissProt: Q3SZN5 Cow

SwissProt: Q9NRF9 Human

SwissProt: Q9JKP7 Mouse

SwissProt: Q642A5 Rat

Unigene: 108112 Human

Unigene: 27444 Mouse

Unigene: 3290 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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