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Rabbit Anti-KRT72/BF350 Conjugated antibody (bs-16831R-BF350)
~~~促销,代码KXJ230206-6~~~
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-16831R-BF350
英文名称 Anti-KRT72/BF350
中文名称 BF350标记的细胞角蛋白72抗体
别    名 CK-72; Cytokeratin-72; K2C72_HUMAN; K6irs; K6IRS2; K72; KB35; Keratin 6 inner root sheath 2; keratin protein K6irs; Keratin type II cytoskeletal 72; Keratin-72; KRT6; KRT6IRS2; Krt72; Type II inner root sheath-specific keratin-K6irs2; Type-II keratin Kb35.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  信号转导  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Mouse,  (predicted: Human, Rat, Rabbit, )
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 56kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human KRT72
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells. The type II keratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This gene encodes a type II keratin that is specifically expressed in the inner root sheath of hair follicles. The type II keratins are clustered in a region of chromosome 12q12-q13. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jun 2009]

Function:
Has a role in hair formation. Specific component of keratin intermediate filaments in the inner root sheath (IRS) of the hair follicle.

Subunit:
Heterotetramer of two type I and two type II keratins.

Tissue Specificity:
Highly expressed in hair follicles from scalp and eyebrow. Also expressed in palmoplantar epidermis. Not expressed in face skin despite the presence of fine hairs histologically. In hair, it is specifically present in the inner root sheath (IRS) of the hair follicle. Present in the IRS cuticle, but not in Henle or Huxley layers of the IRS. In the IRS cuticle, its presence is delayed up to the height of the apex of the dermal papilla (at protein level).

Similarity:
Belongs to the intermediate filament family.

Database links:
  • Entrez Gene: 140807 Human
  • Omim: 608246 Human
  • SwissProt: Q14CN4 Human
  • Unigene: 662013 Human


  • Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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