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Rabbit Anti-GALNTL5/BF647 Conjugated antibody (bs-16228R-BF647)
~~~促销,代码KXJ230206-6~~~
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-16228R-BF647
英文名称 Anti-GALNTL5/BF647
中文名称 BF647标记的GalNAc-TL5蛋白抗体
别    名 GalNAc-T15; GALNACT19; GALNT15; GALNTL5; GLTL5_HUMAN; Polypeptide GalNAc transferase 15; pp-GaNTase 15; Protein-UDP acetylgalactosaminyltransferase 15; Putative polypeptide N-acetylgalactosaminyltransferase-like protein 5; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 15; UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 5.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  免疫学  细胞类型标志物  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Mouse,  (predicted: Human, )
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 51kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GALNTL5
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
GalNAc-TL4 utilizes manganese and calcium as cofactors and is expressed in testis. GalNAc-TL5 may assist with the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on protein receptors and likely catalyzes the initial reaction in O-linked oligosaccharide biosynthesis. Unlike other members of the GalNAc-T subfamily, GalNAc-TL5 does not contain a C-terminal ricin B-type lectin domain. GalNAc-TL5 contains two conserved domains located in its glycosyltransferase region. The N-terminal domain, also known as domain A or GT1 motif, may be involved in manganese coordination and substrate binding while the C-terminal domain, also known as domain B or Gal/GalNAc-T motif, is likely involved in catalytic reactions and UDP-Gal binding. GalNAc-TL5 exists as two alternatively spliced isoforms.

Function:
May catalyze the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor.

Subcellular Location:
Golgi apparatus membrane.

Tissue Specificity:
Expressed in testis.

Similarity:
Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.

Database links:

Entrez Gene: 168391 Human

Omim: 615133 Human

SwissProt: Q7Z4T8 Human

Unigene: 647077 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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