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Rabbit Anti-parathyroid hormone/BF350 Conjugated antibody (bs-10488R-BF350)
~~~促销,代码KXJ230206-6~~~
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-10488R-BF350
英文名称 Anti-parathyroid hormone/BF350
中文名称 BF350标记的甲状旁腺激素抗体
别    名 hPTH; Parathormone; Parathyrin; Parathyroid hormone 1; Parathyroid hormone; PTH; PTH1; PTH1 receptor; PTH1R; PTHR; PTHR1; PTHY_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, )
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 4kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human parathyroid hormone
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 Function:
PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells.

Subunit:
Interacts with PTH1R (via N-terminal extracellular domain).

Subcellular Location:
Secreted.

DISEASE:
Defects in PTH are a cause of familial isolated hypoparathyroidism (FIH) [MIM:146200]; also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism.

Similarity:
Belongs to the parathyroid hormone family.

Database links:

Entrez Gene: 280903 Cow

Entrez Gene: 403986 Dog

Entrez Gene: 5741 Human

Entrez Gene: 19226 Mouse

Entrez Gene: 399502 Pig

Entrez Gene: 24694 Rat

Omim: 168450 Human

SwissProt: P01268 Cow

SwissProt: P52212 Dog

SwissProt: P01270 Human

SwissProt: P01269 Pig

SwissProt: P04089 Rat

Unigene: 37045 Human

Unigene: 284168 Mouse

Unigene: 9768 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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