| 产品编号 | bs-17578R-Cy7 |
| 英文名称 | Anti-OXR1/Cy7 |
| 中文名称 | Cy7标记的抗氧化蛋白1抗体 |
| 别 名 | C7; C7B; Gm1238; Nbla00307; Nucleolar protein C7; Oxidation resistance 1; Oxidation resistance protein 1; Oxr1; OXR1_HUMAN; Putative protein product of Nbla00307; rCG_59825. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 免疫学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, (predicted: Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, ) |
| 产品应用 |
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 98kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human OXR1 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 |
background: Reactive oxygen species (ROS) are highly reactive molecules that are a normal consequence of aerobic metabolism. Cellular ROS damage can induce apoptosis and spontaneous mutagenesis. Oxr1 (Oxidation resistance protein 1) is a 758 amino acid mitochondrial protein that is most likely involved in protection from oxidative damage. Oxr1 is highly conserved from yeast to humans and is specific to eukaryotes.Induced by heat and oxidative stress, the carboxyl-terminal half of Oxr1 is required for its function. Upregulation of superoxide dismutase and catalase was observed in developing drosophila mutants that lacked the gene encoding Oxr1, suggesting that oxidative stress may trigger compensatory protein expression. There are four isoforms of Oxr1 that are produced as a result of alternative splicing events. Function: May be involved in protection from oxidative damage. Subcellular Location: Mitochondrion. Post-translational modifications: Phosphorylated upon DNA damage, probably by ATM or ATR. Similarity: Belongs to the OXR1 family. Contains 1 GRAM domain. Contains 1 LysM repeat. Contains 1 TLD domain. Database links: Entrez Gene: 55074 Human Entrez Gene: 170719 Mouse Omim: 605609 Human SwissProt: Q8N573 Human SwissProt: Q4KMM3 Mouse Unigene: 127286 Human Unigene: 740427 Human Unigene: 254267 Mouse Unigene: 4252 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
