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Rabbit Anti-SERCA3/PE Conjugated antibody (bs-19653R-PE)
~~~促销,代码KXJ230206-6~~~
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-19653R-PE
英文名称 Anti-SERCA3/PE
中文名称 PE标记的肌浆/内质网钙ATP酶3抗体
别    名 Adenosine triphosphatase calcium; AT2A3_HUMAN; Atp2a3; ATPase Ca(2+) transporting ubiquitous; ATPase Ca++ transporting ubiquitous; Calcium pump 3; Calcium translocating P type ATPase; Sarco/endoplasmic reticulum Ca2+ ATPase; Sarcoplasmic/endoplasmic reticulum calcium ATPase 3; SERCA 3; SERCA3; SERCA3b; SR Ca(2+) ATPase 3; SR Ca(2+)-ATPase 3.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  信号转导  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human,  (predicted: Mouse, Chicken, Cow, Xenopus laevis, Xenopus tropicalis)
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 114kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SERCA3
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in calcium sequestration associated with muscular excitation and contraction. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Function:
This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. Transports calcium ions from the cytosol into the sarcoplasmic/endoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction.

Subcellular Location:
Nucleus membrane. Endoplasmic reticulum membrane. Sarcoplasmic reticulum membrane.

Tissue Specificity:
Found in most tissues. Most abundant in thymus, trachea, salivary gland, spleen, bone marrow, lymph node, peripheral leukocytes, pancreas and colon. Also detected in fetal tissues.

Similarity:
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.

Database links:

Entrez Gene: 395707 Chicken

Entrez Gene: 512313 Cow

Entrez Gene: 489 Human

Entrez Gene: 53313 Mouse

Entrez Gene: 25391 Rat

Entrez Gene: 495440 Xenopus laevis

Entrez Gene: 779786 Xenopus tropicalis

Omim: 601929 Human

SwissProt: Q9YGL9 Chicken

SwissProt: Q93084 Human

SwissProt: Q64518 Mouse

SwissProt: P18596 Rat

Unigene: 513870 Human

Unigene: 6306 Mouse

Unigene: 9920 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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