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Rabbit Anti-SLC38A1/PE-Cy5.5 Conjugated antibody (bs-19825R-PE-Cy5.5)
~~~促销,代码KXJ230206-6~~~
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-19825R-PE-Cy5.5
英文名称 Anti-SLC38A1/PE-Cy5.5
中文名称 PE-Cy5.5标记的溶质载体家族蛋白38成员1抗体
别    名 Amino acid transporter A1; Amino acid transporter system A1; ATA 1; ATA1; N-system amino acid transporter 2; NAT 2; NAT2; S38A1_HUMAN; SAT 1; SAT1; SLC38A1; SNAT 1; SNAT1; Sodium-coupled neutral amino acid transporter 1; Solute carrier family 38 member 1; System A amino acid transporter 1; System N amino acid transporter 1.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  细胞生物  信号转导  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Mouse, Rat,  (predicted: Human, Pig, Cow, Guinea Pig, Cat, )
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 54kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SLC38A1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Amino acid transporters play essential roles in the uptake of nutrients, production of energy, chemical metabolism, detoxification, and neurotransmitter cycling. SLC38A1 is an important transporter of glutamine, an intermediate in the detoxification of ammonia and the production of urea. Glutamine serves as a precursor for the synaptic transmitter, glutamate (Gu et al., 2001 [PubMed 11325958]).[supplied by OMIM, Mar 2008]

Function:
Functions as a sodium-dependent amino acid transporter. Mediates the saturable, pH-sensitive and electrogenic cotransport of glutamine and sodium ions with a stoichiometry of 1:1. May also transport small zwitterionic and aliphatic amino acids with a lower affinity. May supply glutamatergic and GABAergic neurons with glutamine which is required for the synthesis of the neurotransmitters glutamate and GABA.

Subcellular Location:
Cell membrane. Restricted to the somatodendritic compartment of neurons. Found in the cellular processes of neurons in the developing brain.

Tissue Specificity:
Expressed in the cerebral cortex by pyramidal and GABAergic neurons, astrocytes and other non-neuronal cells (at protein level). Expressed in placenta, heart, lung, skeletal muscle, spleen, stomach and testis.

Similarity:
Belongs to the amino acid/polyamine transporter 2 family.

Database links:

Entrez Gene: 100725601 Guinea pig

Entrez Gene: 81539 Human

Entrez Gene: 105727 Mouse

Entrez Gene: 170567 Rat

Omim: 608490 Human

SwissProt: Q9H2H9 Human

SwissProt: Q8K2P7 Mouse

SwissProt: Q9JM15 Rat

Unigene: 533770 Human

Unigene: 103568 Mouse

Unigene: 162022 Rat

Unigene: 96943 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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