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Rabbit Anti-PAOX/PE-Cy3 Conjugated antibody (bs-21016R-PE-Cy3)
~~~促销,代码KXJ230206-6~~~
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-21016R-PE-Cy3
英文名称 Anti-PAOX/PE-Cy3
中文名称 PE-Cy3标记的多胺氧化酶PAOX抗体
别    名 DKFZp434J245; MGC45464; PAO; Peroxisomal N(1) acetyl spermine/spermidine oxidase; Peroxisomal N1 acetyl spermine/spermidine oxidase; Polyamine oxidase (exo N4 amino); Polyamine oxidase; RP11 122K13.11.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  细胞生物  信号转导  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Mouse,  (predicted: Human, Rat, Cow, Rabbit, )
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 70/56kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PAOX
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
PAOX is a flavoenzyme which catalyzes the oxidation of N(1)-acetylspermine to spermidine and is thus involved in the polyamine back-conversion. It can also oxidize N(1)-acetylspermidine to putrescine. It does not oxidize spermidine. PAOX plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs. There are eleven named isoforms.

Function:
Flavoenzyme which catalyzes the oxidation of N(1)-acetylspermine to spermidine and is thus involved in the polyamine back-conversion. Can also oxidize N(1)-acetylspermidine to putrescine. Substrate specificity: N(1)-acetylspermine = N(1)-acetylspermidine > N1,N(12)-diacylspermine >> spermine. Does not oxidize spermidine. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs.

Subcellular Location:
Peroxisome. Cytoplasm.

Tissue Specificity:
Widely expressed. Not detected in spleen. Expressed at lower level in neoplastic tissues.

Similarity:
Belongs to the flavin monoamine oxidase family.

Database links:

Entrez Gene: 196743 Human

Entrez Gene: 212503 Mouse

Entrez Gene: 293589 Rat

SwissProt: Q6QHF9 Human

SwissProt: Q8C0L6 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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