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Rabbit Anti-PDE4B/HRP Conjugated antibody (bs-9590R-HRP)
~~~促销,代码KXJ230206-6~~~
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-9590R-HRP
英文名称 Anti-PDE4B/HRP
中文名称 辣根过氧化物酶标记的磷酸二酯酶4B抗体
别    名 5''-cyclic phosphodiesterase 4B; cAMP-specific 3''; cAMP-specific 3',5'-cyclic phosphodiesterase 4B; cAMP-specific 3'5'-cyclic Phosphodiesterase 4B; cAMP-specific phosphodiesterase-4 B isoform; DKFZp686F2182; DPDE4; dunce-like phosphodiesterase E4; MGC126529; OTTHUMP00000010652; OTTHUMP00000010653; OTTHUMP00000010654; OTTHUMP00000010656; OTTHUMP00000232365; PDE 4B; PDE IVB; PDE32; Pde4b; PDE4B_HUMAN; PDE4B5; PDEIVB; Phosphodiesterase 4B; Phosphodiesterase 4B cAMP specific; Phosphodiesterase 4B, cAMP specific (phosphodiesterase E4 dunce homolog, Drosophila); Phosphodiesterase-4B cAMP-specific (dunce (Drosophila)-homolog); Phosphodiesterase-4B cAMP-specific.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  信号转导  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human,  (predicted: Mouse, Rat, )
产品应用 WB=1:500-2000 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 107kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PDE4B
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. The encoded protein regulates the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014]

Function:
Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in mediating central nervous system effects of therapeutic agents ranging from antidepressants to antiasthmatic and anti-inflammatory agents.

Tissue Specificity:
Expressed in brain, heart, lung and skeletal muscle.

Similarity:
Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.

Database links:

Entrez Gene: 5142 Human

Entrez Gene: 18578 Mouse

Entrez Gene: 24626 Rat

Omim: 600127 Human

SwissProt: Q07343 Human

SwissProt: P14646 Rat

Unigene: 198072 Human

Unigene: 20181 Mouse

Unigene: 37733 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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