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Rabbit Anti-Glutaredoxin 1/Cy7 Conjugated antibody (bs-23373R-Cy7)
~~~促销,代码KXJ230206-6~~~
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-23373R-Cy7
英文名称 Anti-Glutaredoxin 1/Cy7
中文名称 Cy7标记的谷氧还蛋白/巯基转移酶抗体
别    名 Glrx; Glrx1; GLRX1_HUMAN; Glutaredoxin; Glutaredoxin-1; Glutaredoxin1; Grx 1; Grx; Grx1; Thioltransferase 1; Thioltransferase; Thioltransferase-1; Thioltransferase1; TTase; TTase 1; TTase-1; TTase1.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  信号转导  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Mouse,  (predicted: Human, Rat, )
产品应用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 12kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Glutaredoxin 1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimer's disease. Multiple alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Aug 2011].

Function:
Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

Subcellular Location:
Cytoplasm.

Similarity:
Belongs to the glutaredoxin family.
Contains 1 glutaredoxin domain.

Database links:

Entrez Gene: 515416 Cow

Entrez Gene: 2745 Human

Entrez Gene: 93692 Mouse

Entrez Gene: 397463 Pig

Entrez Gene: 64045 Rat

Omim: 600443 Human

SwissProt: P10575 Cow

SwissProt: P35754 Human

SwissProt: Q9QUH0 Mouse

SwissProt: P12309 Pig

SwissProt: P12864 Rabbit

SwissProt: Q9ESH6 Rat

Unigene: 28988 Human

Unigene: 712696 Human

Unigene: 25844 Mouse

Unigene: 1484 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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